113028-07-2 Usage
Uses
Used in Pharmaceutical Development:
[2-(1-Benzyl-piperidin-4-yl)-ethyl]-methyl-amine is used as a compound in the pharmaceutical industry for its potential psychoactive or neurological effects. [2-(1-Benzyl-piperidin-4-yl)-ethyl]-methyl-amine's structure, which includes benzyl and piperidine moieties, suggests that it may have applications in the development of drugs targeting the central nervous system.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, [2-(1-Benzyl-piperidin-4-yl)-ethyl]-methyl-amine is used as a subject of study to understand the role of amines in biological systems. This research may contribute to the discovery of new drug candidates and the advancement of our knowledge about the interactions between amines and biological molecules.
Used in Organic Chemistry:
[2-(1-Benzyl-piperidin-4-yl)-ethyl]-methyl-amine is also used in organic chemistry as a compound of interest for its synthesis and purification. Chemists and researchers may explore the compound's properties and reactivity, potentially leading to the development of new synthetic methods or applications in various chemical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 113028-07-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,0,2 and 8 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 113028-07:
(8*1)+(7*1)+(6*3)+(5*0)+(4*2)+(3*8)+(2*0)+(1*7)=72
72 % 10 = 2
So 113028-07-2 is a valid CAS Registry Number.
113028-07-2Relevant academic research and scientific papers
Novel [2-(4-piperidinyl)ethyl](thio)ureas: Synthesis and antiacetylcholinesterase activity
Vidaluc,Calmel,Bigg,Carilla,Stenger,Chopin,Briley
, p. 689 - 695 (2007/10/02)
A series of 1-ar(o)yl-3-[2-(1-benzyl-4-piperidinyl)ethyl](thio)urea derivatives was synthesized and evaluated for antiacetylcholinesterase activity. Most aroyl(thio)urea derivatives showed potent inhibitory activity in the sub-micromolar range. A comparable potency was obtained with the aryl(thio)urea analogues by replacing the phenyl with a 2-pyridyl group. The substituted guanidine variations proved to be almost inactive whereas the nitroethylene analogues appeared to be quite efficient. These results were interpreted in terms of the preferential cis-trans conformation of the aroyl(thio)urea and 2-pyridyl(thio)urea moieties involving the existence of hydrogen bonding. In vivo experiments showed that compound 7m had maximal antiamnestic activity at 0.03 mg/kg with a therapeutic ratio greater than 1000, while cholinergic side effects were only seen at doses 100-fold the maximally effective antiamnestic dose. Compound 7m represents a potentially interesting antidementia agent.
