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1130321-48-0

C27H19ClN6O4S is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1130321-48-0 Structure

  • Basic information

    1. Product Name: C27H19ClN6O4S
    2. Synonyms:
    3. CAS NO:1130321-48-0
    4. Molecular Formula:
    5. Molecular Weight: 559.005
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1130321-48-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C27H19ClN6O4S(CAS DataBase Reference)
    10. NIST Chemistry Reference: C27H19ClN6O4S(1130321-48-0)
    11. EPA Substance Registry System: C27H19ClN6O4S(1130321-48-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1130321-48-0(Hazardous Substances Data)

1130321-48-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1130321-48-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,3,0,3,2 and 1 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1130321-48:
(9*1)+(8*1)+(7*3)+(6*0)+(5*3)+(4*2)+(3*1)+(2*4)+(1*8)=80
80 % 10 = 0
So 1130321-48-0 is a valid CAS Registry Number.

1130321-48-0Downstream Products

1130321-48-0Relevant articles and documents

II. Novel HCV NS5B polymerase inhibitors: Discovery of indole C2 acyl sulfonamides

Anilkumar, Gopinadhan N.,Selyutin, Oleg,Rosenblum, Stuart B.,Zeng, Qingbei,Jiang, Yueheng,Chan, Tin-Yau,Pu, Haiyan,Wang, Li,Bennett, Frank,Chen, Kevin X.,Lesburg, Charles A.,Duca, Jose,Gavalas, Stephen,Huang, Yuhua,Pinto, Patrick,Sannigrahi, Mousumi,Velazquez, Francisco,Venkatraman, Srikanth,Vibulbhan, Bancha,Agrawal, Sony,Ferrari, Eric,Jiang, Chuan-Kui,Huang,Shih, Neng-Yang,George Njoroge,Kozlowski, Joseph A.

scheme or table, p. 713 - 717 (2012/02/04)

Development of SAR at the C2 position of indole lead 1, a palm site inhibitor of HCV NS5B polymerase (NS5B IC50 = 0.053 μM, replicon EC50 = 4.8 μM), is described. Initial screening identified an acyl sulfonamide moiety as an isostere for the C2 carboxylic acid group. Further SAR investigation resulted in identification of acyl sufonamide analog 7q (NS5B IC50 = 0.039 μM, replicon EC50 = 0.011 μM) with >100-fold improved replicon activity.

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