113036-11-6 Usage
General Description
MONO-ETHYL (R)-3-ACETOXYGLUTARATE is a chemical compound that belongs to the group of acetoxy esters. It is a clear, colorless liquid with a molecular formula C8H12O6 and a molecular weight of 204.18 g/mol. MONO-ETHYL (R)-3-ACETOXYGLUTARATE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has potential applications in the field of organic chemistry and biochemistry due to its ability to undergo various chemical reactions, such as esterification and hydrolysis. Additionally, it is important to handle this chemical with care as it has the potential to cause irritation to the skin, eyes, and respiratory system if proper safety precautions are not taken.
Check Digit Verification of cas no
The CAS Registry Mumber 113036-11-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,0,3 and 6 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 113036-11:
(8*1)+(7*1)+(6*3)+(5*0)+(4*3)+(3*6)+(2*1)+(1*1)=66
66 % 10 = 6
So 113036-11-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H14O6/c1-3-14-9(13)5-7(4-8(11)12)15-6(2)10/h7H,3-5H2,1-2H3,(H,11,12)/t7-/m1/s1
113036-11-6Relevant articles and documents
Integrated Biocatalysis in Multistep Drug Synthesis without Intermediate Isolation: A de Novo Approach toward a Rosuvastatin Key Building Block
Metzner, Richard,Hummel, Werner,Wetterich, Frank,K?nig, Burghard,Gr?ger, Harald
supporting information, p. 635 - 638 (2015/06/30)
In this contribution, we report the chemoenzymatic preparation of a key building block for the active pharmaceutical ingredient rosuvastatin, one of the "top 5 blockbuster drugs" with a worldwide market value of 6.25 billion USD in 2012, via a seven-step synthesis without isolation of intermediates and with incorporation of two highly efficient biotransformations. This chemoenzymatic process reaches excellent space-time yields by using high substrate concentrations (several hundred grams per liter), emphasizing the potential of biocatalysis for industrial processes related to pharmaceutical drug synthesis and the compatibility of enzyme chemistry with classical organic synthesis.
