1130601-53-4Relevant academic research and scientific papers
First example of an organocatalytic asymmetric Mannich reaction between aldimines of glycinates and sulphonyl imines
Wu, Lei,Li, Guangxun,He, Migu,Wang, Yingwei,Zhao, Gang,Tang, Zhuo
, p. 769 - 772 (2016)
The catalytic enantioselective Mannich-type reaction between glycinate Schiff base and imines has been one of the most efficient routes for accessing α,β-diamino acids. However, the glycinate Schiff bases used in the references were almost ketimines. Only
Reversal of enantioselectivity using tethered bisguanidine catalysts in the aza-Henry reaction
Lovick, Helena M.,Michael, Forrest E.
supporting information; experimental part, p. 1016 - 1019 (2009/05/27)
A series of chiral guanidines were synthesized and shown to efficiently catalyze the aza-Henry reaction. Modifications of the catalyst structure revealed important selectivity trends as well as an intriguing reversal in stereoselectivity with bisguanidine
