1130799-04-0Relevant articles and documents
Palladium-catalyzed indole and azaindole synthesis by direct annulation of electron-poor o-chloroanilines and o-chloroaminopyridines with aldehydes
Xu, Zhengren,Hu, Weimin,Zhang, Fengying,Li, Qingjiang,Lue, Zhiyao,Zhang, Lihe,Jia, Yanxing
experimental part, p. 3981 - 3987 (2009/05/27)
A practical process for the synthesis of 2-unsubstituted indoles and azaindoles has been developed by the palladium-catalyzed direct annulation of electron-poor o-chloro/bromoanilines and o-chloroaminopyridines with aldehydes. Coupled with the previous results of Jia and Zhu, this allows rapid access to a variety of 2-unsubstituted indoles and azaindoles starting from simple and easily accessible precursors. Georg Thieme Verlag Stuttgart.