1130816-53-3Relevant academic research and scientific papers
Highly enantioselective transfer hydrogenation of racemic α-substituted β-keto sulfonamides: Via dynamic kinetic resolution
Xiong, Zhichao,Pei, Chengfeng,Xue, Peng,Lv, Hui,Zhang, Xumu
, p. 3883 - 3886 (2018)
Highly enantioselective transfer hydrogenation of β-keto sulfonamides was developed via dynamic kinetic resolution using a chiral Ru(ii) catalyst with an azeotropic solution of HCO2H/Et3N as a hydrogen donor, affording α-substituted β-hydroxyl sulfonamides in good yields with excellent diastereo- and enantioselectivities. This method is featured with mild conditions, easy operation, and a broad substrate scope, which make it possible to find wide applications in the synthesis of natural products and biologically active compounds containing the α-substituted β-hydroxyl sulfonamide core.
Dynamic kinetic resolution of β-keto sulfones via asymmetric transfer hydrogenation
Ding, Zhenhua,Yang, Jin,Wang, Ting,Shen, Zongxuan,Zhang, Yawen
supporting information; experimental part, p. 571 - 573 (2009/06/17)
The dynamic kinetic resolution of β-keto sulfones was achieved via asymmetric transfer hydrogenation using (S,S)-RuCl[N-(tosyl)-1,2- diphenylethylenediamine](p-cymene) in the presence of formic acid and triethylamine afforded the desired products in good
