113084-12-1

Basic information

• Product Name: (1R,2R)-2-hydroxy-2,6,6-trimethyl-1-cyclohexanemethanol
• Synonyms: (1R,2R)-2-hydroxy-2,6,6-trimethyl-1-cyclohexanemethanol
• CAS NO: 113084-12-1
• Molecular Weight: 172.268
• Mol File: 113084-12-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2R)-2-hydroxy-2,6,6-trimethyl-1-cyclohexanemethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R)-2-hydroxy-2,6,6-trimethyl-1-cyclohexanemethanol(113084-12-1)
• EPA Substance Registry System: (1R,2R)-2-hydroxy-2,6,6-trimethyl-1-cyclohexanemethanol(113084-12-1)

Safety Data

• Hazardous Substances Data: 113084-12-1(Hazardous Substances Data)

Downstream Products

• 113084-08-5 (-)-2-hydroxy-2,6,6-trimethyl-1-cyclohexanecarbaldehyde 
• 73925-69-6 (-)-(1'S)-2',3'-dihydro-2'-hydroxy-α-ionone 
• 64129-96-0 (S)-(+)-(E)-4-(2',2'-dimethyl-6'-methylene-1'-cyclohexyl)but-3-en-2-one 
• 24190-33-8 (+)-(S)-dihydro-γ-ionone 
• 24190-29-2 (R)-α-ionone 

Relevant articles and documents

Synthesis and Absolute Stereochemistry of Chiral γ-Ionone and Dihydro-γ-ionone

The optical resolution of (+/-)-α-cyclogeranic acid (4) with (-)-α-methylbenzylamine gave (-)-(S)-α-cyclogeranic acid (4).Epoxidation of (-)-(S)-methyl α-cyclogeranate (5), followed by reduction with lithium aluminium hydride, gave mainly (-)-(1R,2R)-2-hydroxy-2,6,6-trimethyl-1-cyclohexanemethanol (7b), which was oxidized with pyridinium chlorochromate to give (-)-hydroxyaldehyde 8.The reaction of aldehyde 8 with 2-oxopropylidenetriphenylphosphorane gave (-)-(1'S,2'R)-2',3'-dihydro-2'-hydroxy-α-ionone (9).The thermal decomposition of (1'S)-2'-acetoxy-2',3'-dihydro-α-ionone (10) gave (-)-(S)-α-ionone (2) and (+)-(S)-γ-ionone (1).The partial hydrogenation of (+)-(S)-γ-ionone (1) gave (+)-(S)-dihydro-γ-ionone (3).