113089-01-3Relevant academic research and scientific papers
METHOD FOR PRODUCING PHOSPHORIC ACID ESTER AMIDE
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Paragraph 0105-0106; 0112, (2016/12/07)
PROBLEM TO BE SOLVED: To provide a method for producing phosphoric acid ester amide in which by not using excess aromatic amine with respect to phosphorochloridate, that is, by using aromatic amine by 0.8 to 1.2 equivalents with respect to phosphorochlori
Kinetics and mechanism of the anilinolysis of dibutyl chlorophosphate in acetonitrile
Hoque, Md. Ehtesham Ul,Lee, Hai Whang
scheme or table, p. 663 - 669 (2012/05/19)
The nucleophilic substitution reactions of dibutyl chlorophosphate (3) with substituted anilines (XC6H4NH2) and deuterated anilines (XC6H4ND2) are investigated kinetically in acetonitrile at 55.0 °C. The obtained deuterium kinetic isotope effects (DKIEs; kH/kD) are secondary inverse (kH/kD = 0.86-0.97) with the strongly basic anilines while primary normal (kH/kD = 1.04-1.10) with the weakly basic anilines. The DKIEs, steric effects of the two ligands, activation parameters, cross-interaction constants, variation trends of the kH/kD values with X, and mechanism are discussed for the anilinolyses of the nine (R1O)(R2O)P(=O)Cl-type chlorophosphates. A concerted mechanism is proposed with a backside nucleophilic attack transition state for the strongly basic anilines and with a frontside attack involving a hydrogen-bonded four-center-type transition state for the weakly basic anilines on the basis of the magnitudes, secondary inverse and primary normal, and variation trends of the kH/kD values with X.
Preparation of Sterically Hindered Phosphoramidates
Talley, John J.
, p. 221 - 222 (2007/10/02)
Treatment of phosphorus oxychloride with two equivalents of 2,6-dimethylphenol in the presence of magnesium chloride produced the sterically hindered bis(2,6-dimethylphenyl) chlorophosphate in excellent yield.The diaryl phosphorochloridate reacted with a
