1131-87-9

Basic information

• Product Name: 1-(1-BENZOTHIOPHEN-5-YL)-2-BROMO-1-ETHANONE
• Synonyms: 1-(BENZOTHIEN-5-YL)-2-BROMOETHANONE;1-(1-BENZOTHIOPHEN-5-YL)-2-BROMO-1-ETHANONE;1-(Benzo[b]thiophen-5-yl)-2-bromoethan-1-one;1-(Benzo[b]thiophen-5-yl)-2-bromoethan-1-one 97%;5-(Bromoacetyl)benzo[b]thiophene 97%;1-(1-benzo[b]thiophen-5-yl)-2-broMo-1-ethanone;6-BROMO-3-FLUORO-2-METHYLPHENOL;5-(Bromoacetyl)benzo[b]thiophene97%
• CAS NO: 1131-87-9
• Molecular Formula: C₁₀H₇BrOS
• Molecular Weight: 255.13
• Mol File: 1131-87-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 48 °C
• Boiling Point: 118 °C
• Flash Point: 166.7 °C
• Appearance: /
• Density: 1.617 g/cm³
• Vapor Pressure: 3.96E-05mmHg at 25°C
• Refractive Index: 1.689
• CAS DataBase Reference: 1-(1-BENZOTHIOPHEN-5-YL)-2-BROMO-1-ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-BENZOTHIOPHEN-5-YL)-2-BROMO-1-ETHANONE(1131-87-9)
• EPA Substance Registry System: 1-(1-BENZOTHIOPHEN-5-YL)-2-BROMO-1-ETHANONE(1131-87-9)

Safety Data

• Hazard Codes: C
• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 1131-87-9(Hazardous Substances Data)

Usage

General Description

1-(1-benzothiophen-5-yl)-2-bromo-1-ethanone is a chemical compound that contains a benzothiophene ring and a bromoethyl ketone. It is commonly used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. The benzothiophene ring is known for its potential biological activities, making this compound of interest in drug discovery and development. The bromoethyl ketone group also adds versatility to the molecule, allowing for further modification and functionalization. Overall, 1-(1-benzothiophen-5-yl)-2-bromo-1-ethanone has potential in various chemical and pharmaceutical applications.

InChI:InChI=1/C10H7BrOS/c11-6-9(12)7-1-2-10-8(5-7)3-4-13-10/h1-5H,6H2

Upstream product

• 1128-88-7 5-acetylbenzothiophene 

Downstream Products

• 877264-39-6 C₁₉H₁₉NO₂S 
• 877264-27-2 C₁₉H₁₉NO₂S 
• 877264-42-1 C₁₉H₁₈INO₂S 
• 877264-28-3 C₁₉H₂₁NO₂S 
• 1056209-39-2 (3R,4R)-3-(2-benzo[b]thiophen-5-yl-2-oxoethylthio)-1-(4-iodophenyl)-4-[4-(1,1,2,2-tetramethyl-1-silapropoxy)phenyl]azetidin-2-one 

Relevant articles and documents

Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin

The compounds of the present invention are represented by the chemical structure found in Formula (I): wherein: the carbon atom designated * is in the R or S configuration; and X is a fused bicyclic carbocycle or heterocycle selected from the group consisting of benzofuranyl, benzo[b]thiophenyl, benzoisothiazolyl, benzoisoxazolyl, indazolyl, indolyl, isoindolyl, indolizinyl, benzoimidazolyl, benzooxazolyl, benzothiazolyl, benzotriazolyl, imidazo[1,2-a]pyridinyl, pyrazolo[1,5-a]pyridinyl, [1,2,4]triazolo[4,3-a]pyridinyl, thieno[2,3-b]pyridinyl, thieno[3,2-b]pyridinyl, 1H-pyrrolo[2,3-b]pyridinyl, indenyl, indanyl, dihydrobenzocycloheptenyl, tetrahydrobenzocycloheptenyl, dihydrobenzothiophenyl, dihydrobenzofuranyl, indolinyl, naphthyl, tetrahydronaphthyl, quinolinyl, isoquinolinyl, 4H-quinolizinyl, 9aH-quinolizinyl, quinazolinyl, cinnolinyl, phthalazinyl, quinoxalinyl, benzo[1,2,3]triazinyl, benzo[1,2,4]triazinyl, 2H-chromenyl, 4H-chromenyl, and a fused bicyclic carbocycle or fused bicyclic heterocycle optionally substituted with substituents (1 to 4 in number) as defined in R14; with R1, R2, R3, R4, R5, R6, R7, R8, and R14 defined herein.