1131-87-9

Usage

Uses

Used in Pharmaceutical Industry:
1-(1-BENZOTHIOPHEN-5-YL)-2-BROMO-1-ETHANONE is used as a synthetic intermediate for the creation of various pharmaceuticals due to its potential biological activities and the ability to modify and functionalize the molecule for specific therapeutic applications.
Used in Organic Chemistry:
In the field of organic chemistry, 1-(1-BENZOTHIOPHEN-5-YL)-2-BROMO-1-ETHANONE serves as a versatile building block for the synthesis of complex organic compounds, leveraging the reactivity of both the benzothiophene ring and the bromoethyl ketone group for further chemical transformations.

InChI:InChI=1/C10H7BrOS/c11-6-9(12)7-1-2-10-8(5-7)3-4-13-10/h1-5H,6H2

Upstream product

• 1128-88-7 5-acetylbenzothiophene 

Downstream Products

• 877264-28-3 C₁₉H₂₁NO₂S 
• 1056209-39-2 (3R,4R)-3-(2-benzo[b]thiophen-5-yl-2-oxoethylthio)-1-(4-iodophenyl)-4-[4-(1,1,2,2-tetramethyl-1-silapropoxy)phenyl]azetidin-2-one 
• 877264-42-1 C₁₉H₁₈INO₂S 
• 877264-27-2 C₁₉H₁₉NO₂S 
• 877264-39-6 C₁₉H₁₉NO₂S 

Relevant academic research and scientific papers

Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin

The compounds of the present invention are represented by the chemical structure found in Formula (I): wherein: the carbon atom designated * is in the R or S configuration; and X is a fused bicyclic carbocycle or heterocycle selected from the group consisting of benzofuranyl, benzo[b]thiophenyl, benzoisothiazolyl, benzoisoxazolyl, indazolyl, indolyl, isoindolyl, indolizinyl, benzoimidazolyl, benzooxazolyl, benzothiazolyl, benzotriazolyl, imidazo[1,2-a]pyridinyl, pyrazolo[1,5-a]pyridinyl, [1,2,4]triazolo[4,3-a]pyridinyl, thieno[2,3-b]pyridinyl, thieno[3,2-b]pyridinyl, 1H-pyrrolo[2,3-b]pyridinyl, indenyl, indanyl, dihydrobenzocycloheptenyl, tetrahydrobenzocycloheptenyl, dihydrobenzothiophenyl, dihydrobenzofuranyl, indolinyl, naphthyl, tetrahydronaphthyl, quinolinyl, isoquinolinyl, 4H-quinolizinyl, 9aH-quinolizinyl, quinazolinyl, cinnolinyl, phthalazinyl, quinoxalinyl, benzo[1,2,3]triazinyl, benzo[1,2,4]triazinyl, 2H-chromenyl, 4H-chromenyl, and a fused bicyclic carbocycle or fused bicyclic heterocycle optionally substituted with substituents (1 to 4 in number) as defined in R14; with R1, R2, R3, R4, R5, R6, R7, R8, and R14 defined herein.