1131040-29-3Relevant academic research and scientific papers
New mixed Li/Mg and Li/Mg/Zn amides for the chemoselectlve metallation of arenes and heteroarenes
Rohbogner, Christoph J.,Wunderlich, Stefan H.,Clososki, Giuliano C.,Knochel, Paul
experimental part, p. 1781 - 1795 (2009/09/05)
New mixed Li/Mg and Li/Mg/Zn amides have been synthesized starting from readily prepared secondary amines. They allow a highly chemoselective directed magnesiation or zincation of various polyfunctional aromatics and heteroaromatics. The kinetic basicity, solubility and stability of these new bases have been compared with those of the corresponding 2,2,6,6- tetramethylpiperamide-derived bases. Wiley-VCH Verlag GmbH & Co. KGaA.
Direct zincation of functionalized aromatics and heterocycles by using a magnesium base in the presence of ZnCl2
Dong, Zhibing,Clososki, Giuliano C.,Wunderlich, Stefan H.,Unsinn, Andreas,Li, Jinshan,Knochel, Paul
experimental part, p. 457 - 468 (2009/06/24)
A wide range of polyfunctional aryl and heteroaryl zinc reagents were efficiently prepared in THF by using (TMP)2:Mg·2LiCl (TMP = 2,2,6,6-tetramethylpiperamidyl) in the presence of ZnCl2. The possible pathways of this metalation proc
