1131041-58-1 Usage
General Description
3-methyl-1H-pyrazolo[3,4-b]pyridine is a chemical compound with the molecular formula C7H6N2. It is a heterocyclic compound containing a pyrazole and a pyridine ring. This chemical has a molecular weight of 118.14 g/mol and a melting point of 117-119 °C. 3-methyl-1H-pyrazolo[3,4-b]pyridine is used in the synthesis of pharmaceuticals and has potential applications in medicinal chemistry and drug discovery. It is also used as a building block in organic synthesis for the production of various compounds. This chemical has a wide range of potential applications and is of interest to researchers in the fields of chemistry, pharmacology, and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 1131041-58-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,3,1,0,4 and 1 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1131041-58:
(9*1)+(8*1)+(7*3)+(6*1)+(5*0)+(4*4)+(3*1)+(2*5)+(1*8)=81
81 % 10 = 1
So 1131041-58-1 is a valid CAS Registry Number.
1131041-58-1Relevant articles and documents
2,3,5-Trisubstituted pyridines as selective AKT inhibitors. Part II: Improved drug-like properties and kinase selectivity from azaindazoles
Lin, Hong,Yamashita, Dennis S.,Zeng, Jin,Xie, Ren,Verma, Sharad,Luengo, Juan I.,Rhodes, Nelson,Zhang, Shuyun,Robell, Kimberly A.,Choudhry, Anthony E.,Lai, Zhihong,Kumar, Rakesh,Minthorn, Elisabeth A.,Brown, Kristin K.,Heerding, Dirk A.
scheme or table, p. 679 - 683 (2010/07/06)
A novel series of AKT inhibitors containing 2,3,5-trisubstituted pyridines with novel azaindazoles as hinge binding elements are described. Among these, the 4,7-diazaindazole compound 2c has improved drug-like properties and kinase selectivity than those of indazole 1, and displays greater than 80% inhibition of GSK3β phosphorylation in a BT474 tumor xenograft model in mice.
