113105-86-5

Basic information

• Product Name: 1-(acridin-9-yloxy)-3-(morpholin-4-yl)propan-2-ol
• CAS NO: 113105-86-5
• Molecular Formula: C₂₀H₂₂N₂O₃
• Molecular Weight: 338.4003
• Mol File: 113105-86-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 580.2°C at 760 mmHg
• Flash Point: 304.7°C
• Density: 1.251g/cm³
• Vapor Pressure: 2.64E-14mmHg at 25°C
• Refractive Index: 1.654
• CAS DataBase Reference: 1-(acridin-9-yloxy)-3-(morpholin-4-yl)propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(acridin-9-yloxy)-3-(morpholin-4-yl)propan-2-ol(113105-86-5)
• EPA Substance Registry System: 1-(acridin-9-yloxy)-3-(morpholin-4-yl)propan-2-ol(113105-86-5)

Safety Data

• Hazardous Substances Data: 113105-86-5(Hazardous Substances Data)

Upstream product

• 643-62-9 9-acridinol 
• 110-91-8 morpholine 
• 113105-85-4 9-(2,3-epoxypropyloxy)acridine 

Relevant articles and documents

Synthesis of 9-Substituted-oxy Acridine and 1,2,3,4-Tetrahydroacridine Derivatives as Potential Biodynamic Agents

9-(3-Substituted-2-hydroxypropyloxy)acridines (5-11) and 9-(2-hydroxy-3-morpholinopropyloxy)-1,2,3,4-tetrahydroacridine (17) have been synthesised via the epoxy intermediates 9-(2,3-epoxypropyloxy)acridine (4) and the corresponding tetrahydroacridine (15).A few 9-(thiocyanato, phenylcarbamoyloxy and substituted amino)-tetrahydroacridines (21, 23 and 24-27) and 2,3-epoxypropyl N-phenylanthranilate (3) have also been prepared.Compounds 15, 17, 22, 24 and 26 show in vitro antiamoebic activity at 16 - 62.5 μg/ml dose while the standard drug metronidazole is found antiamoebic at 4 μg/ml.Compounds 25-27 exhibit local anaesthetic activity at 0.2percent concentration.