113105-90-1 Usage
General Description
1-(acridin-9-yloxy)-3-[4-(3-chlorophenyl)piperazin-1-yl]propan-2-ol is a chemical compound that contains an acridine moiety, a piperazine moiety, and an alcohol group. The acridine moiety is a polycyclic aromatic hydrocarbon that has been used in various medicinal applications, including as an anti-tumor agent. The piperazine moiety is a common pharmacophore in many drugs, and the presence of a chlorine atom on the phenyl ring enhances the compound's pharmacological properties. The alcohol group gives the compound a hydrophilic character, making it suitable for use in aqueous formulations. The compound's structure and functional groups make it a potential candidate for the development of new pharmaceuticals with a range of therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 113105-90-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,1,0 and 5 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 113105-90:
(8*1)+(7*1)+(6*3)+(5*1)+(4*0)+(3*5)+(2*9)+(1*0)=71
71 % 10 = 1
So 113105-90-1 is a valid CAS Registry Number.
113105-90-1Relevant articles and documents
Synthesis of 9-Substituted-oxy Acridine and 1,2,3,4-Tetrahydroacridine Derivatives as Potential Biodynamic Agents
Asthana, Pratibha,Prasad, Mohan,Rastogi, Shri Nivas
, p. 330 - 334 (2007/10/02)
9-(3-Substituted-2-hydroxypropyloxy)acridines (5-11) and 9-(2-hydroxy-3-morpholinopropyloxy)-1,2,3,4-tetrahydroacridine (17) have been synthesised via the epoxy intermediates 9-(2,3-epoxypropyloxy)acridine (4) and the corresponding tetrahydroacridine (15).A few 9-(thiocyanato, phenylcarbamoyloxy and substituted amino)-tetrahydroacridines (21, 23 and 24-27) and 2,3-epoxypropyl N-phenylanthranilate (3) have also been prepared.Compounds 15, 17, 22, 24 and 26 show in vitro antiamoebic activity at 16 - 62.5 μg/ml dose while the standard drug metronidazole is found antiamoebic at 4 μg/ml.Compounds 25-27 exhibit local anaesthetic activity at 0.2percent concentration.
