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Guanidine, N-(3-methoxypropyl)-N'-[5-(2-methylphenyl)-1,3,4-thiadiazol-2-yl]-, monohydrochloride is a chemical compound that integrates guanidine, a nitrogenous organic compound, with a 1,3,4-thiadiazole ring system featuring a 2-methylphenyl group. This monohydrochloride salt is recognized for its high water solubility, which may enhance its bioavailability and cellular uptake. It is primarily utilized in pharmaceutical research as a potential anticancer agent due to its reported inhibitory effects on cell proliferation.

113113-08-9

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113113-08-9 Usage

Uses

Used in Pharmaceutical Research:
Guanidine, N-(3-methoxypropyl)-N'-[5-(2-methylphenyl)-1,3,4-thiadiazol-2-yl]-, monohydrochloride is used as a potential anticancer agent for its ability to inhibit cell proliferation. Guanidine,
N-(3-methoxypropyl)-N'-[5-(2-methylphenyl)-1,3,4-thiadiazol-2-yl]-,
monohydrochloride's structure and properties make it a candidate for further studies to explore its pharmacological properties and therapeutic applications in cancer treatment.
Used in Drug Development:
In the drug development industry, Guanidine, N-(3-methoxypropyl)-N'-[5-(2-methylphenyl)-1,3,4-thiadiazol-2-yl]-, monohydrochloride is used as a lead compound for the design and synthesis of new anticancer drugs. Its unique chemical structure and potential biological activity provide a foundation for developing novel therapeutic agents that could target various types of cancer.
Used in Bioavailability Enhancement:
Due to its high water solubility, Guanidine, N-(3-methoxypropyl)-N'-[5-(2-methylphenyl)-1,3,4-thiadiazol-2-yl]-, monohydrochloride is used to improve the bioavailability of other poorly soluble drug candidates. This property can be leveraged to enhance the absorption and distribution of these drugs in the body, potentially leading to more effective treatments.
Further studies are necessary to fully understand the pharmacological properties and potential therapeutic applications of Guanidine, N-(3-methoxypropyl)-N'-[5-(2-methylphenyl)-1,3,4-thiadiazol-2-yl]-, monohydrochloride, as well as to optimize its use in various medical and pharmaceutical applications.

Check Digit Verification of cas no

The CAS Registry Mumber 113113-08-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,1,1 and 3 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 113113-08:
(8*1)+(7*1)+(6*3)+(5*1)+(4*1)+(3*3)+(2*0)+(1*8)=59
59 % 10 = 9
So 113113-08-9 is a valid CAS Registry Number.

113113-08-9Downstream Products

113113-08-9Relevant academic research and scientific papers

Antihypertensive thiadiazoles. 2. Vasodilator activity of some 2-aryl-5-guanidino-1,3,4-thiadiazoles

Turner,Myers,Gadie,Hale,Horsley,Nelson,Pape,Saville,Doxey,Berridge

, p. 906 - 913 (2007/10/02)

Some 2-aryl-5-guanidino-(or N-substituted guanidino)-1,3,4-thiadiazoles and closely related analogues were found to lower blood pressure in metacorticoid (DOCA) hypertensive rats. In the unsubstituted guanidines that exhibited low toxicity, optimum activi

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