113113-15-8Relevant articles and documents
Antihypertensive thiadiazoles. 2. Vasodilator activity of some 2-aryl-5-guanidino-1,3,4-thiadiazoles
Turner,Myers,Gadie,Hale,Horsley,Nelson,Pape,Saville,Doxey,Berridge
, p. 906 - 913 (2007/10/02)
Some 2-aryl-5-guanidino-(or N-substituted guanidino)-1,3,4-thiadiazoles and closely related analogues were found to lower blood pressure in metacorticoid (DOCA) hypertensive rats. In the unsubstituted guanidines that exhibited low toxicity, optimum activi