113118-86-8

Basic information

• Product Name: 3-Pyridinecarboxaldehyde, 5-methoxy-4-methyl- (9CI)
• Synonyms: 3-Pyridinecarboxaldehyde, 5-methoxy-4-methyl- (9CI);5-Methoxy-4-Methylnicotinaldehyde;5-Methoxy-4-methylpyridine-3-carboxaldehy
• CAS NO: 113118-86-8
• Molecular Formula: C8H9NO2
• Molecular Weight: 151.16256
• Product Categories: ALDEHYDE
• Mol File: 113118-86-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-Pyridinecarboxaldehyde, 5-methoxy-4-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxaldehyde, 5-methoxy-4-methyl- (9CI)(113118-86-8)
• EPA Substance Registry System: 3-Pyridinecarboxaldehyde, 5-methoxy-4-methyl- (9CI)(113118-86-8)

Safety Data

• Hazardous Substances Data: 113118-86-8(Hazardous Substances Data)

Usage

General Description

3-Pyridinecarboxaldehyde, 5-methoxy-4-methyl- (9CI) is a chemical compound with a molecular formula of C8H9NO2. It is a derivative of pyridinecarboxaldehyde, containing a methoxy group at the 5 position and a methyl group at the 4 position. 3-Pyridinecarboxaldehyde, 5-methoxy-4-methyl- (9CI) is used in various chemical and pharmaceutical applications, including as a building block in the synthesis of organic compounds and as a reagent in organic chemistry. It may also have potential biological activities, although further research is needed to fully understand its properties and potential uses.

Upstream product

• 113118-83-5 5-methoxypyridine-3-carboxaldehyde 
• 74-88-4 methyl iodide 
• 50720-12-2 3-bromo-5-methoxypyridine 
• 625-92-3 3,5-dibromopyridine 
• 113118-88-0 3-Methoxy-4-methyl-4H-pyridine-1-carboxylic acid phenyl ester 
• 113118-80-2 3-Formyl-5-methoxy-4-methyl-4H-pyridine-1-carboxylic acid phenyl ester 
• 7295-76-3 3-methoxypyridine 

Relevant articles and documents

Lithiation of Methoxypyridines Directed by α-Amino Alkoxides

The addition of methoxypyridinecarboxaldehydes to certain lithium dialkylamides gave α-amino alkoxides in situ that were ring-lithiated with alkyllithium bases.Alkylation and hydrolysis on workup provided ring-substituted methoxypyridinecarboxaldehydes via a one-pot reaction.The one-pot methylation of isomeric methoxypyridinecarboxaldehydes was examined.The regioselectivity of the lithiation-methylation was dependent on the aldehyde, the amine component of the α-amino alkoxide, and the metalation conditions.When lithiated N,N,N'-trimethylethylenediamine was used as the amine component of the α-amino alkoxide, methylation generally occured ortho to the aldehyde function.The analogous reactions using lithium N-methylpiperazide as the amine component gave substitution next to the methoxy group.Several new methylated methoxypyridinecarboxaldehydes were prepared in a regioselective manner by using this one-pot procedure.