1131344-00-7Relevant academic research and scientific papers
Multicomponent one pot synthesis of C-glucosides of 1-azaindolizines
Kumar, Banty,Shankar, Bhawani,Kumar, Sandeep,Maity, Jyotirmoy,Prasad, Ashok K.
, p. 2853 - 2859 (2020)
A protocol based on Groebke-Blackburn-Bienayame (GBB) multicomponent reaction has been developed for efficient and atom economical synthesis of C-glucosides of 1-azaindolizine, i.e. 2-(β-D-glucopyranosyl)-3-N-alkylamino-1-azaindolizine. Thus, a series of fourteen novel 2-(β-D-glucopyranosyl)-3-N-alkylamino-1-azaindolizines have been synthesized in moderate to good yields by reaction of a perbenzylated β-C-glucopyranosyl aldehyde with differently substituted 2-aminopyridines and alkyl isocyanides using InCl3 as acid catalyst. All synthesized β-C-glucosides were unambiguously characterized with the help of spectroscopic (IR, 1H-NMR, 13C-NMR and mass spectra) data analysis.
Synthesis of Pro-XylaneTM: A new biologically active C-glycoside in aqueous media
Cavezza, Alexandre,Boulle, Christophe,Gueguiniat, Amelie,Pichaud, Patrick,Trouille, Simon,Ricard, Louis,Dalko-Csiba, Maria
scheme or table, p. 845 - 849 (2009/10/02)
The scope and limitation of Lubineau's reaction were evaluated for the synthesis of C-glycosides (compounds 1-13). Further transformation of side chain carbonyl was also achieved (compounds 16-23). Optimization of these two steps was investigated in xylos
