1131410-85-9

Basic information

• Product Name: 7-Chloro-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
• Synonyms: 7-Chloro-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine;2-Amino-7-chloro-[1,2,4]triazolo[1,5-a]pyridine;7-chloro-[1,2,4]triazolo[1,5-a]pyridin-2-amine
• CAS NO: 1131410-85-9
• Molecular Formula: C6H5ClN4
• Molecular Weight: 168.5837
• Mol File: 1131410-85-9.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Density: 1.71
• Storage Temp.: 2-8°C
• PKA: 4.32±0.30(Predicted)
• CAS DataBase Reference: 7-Chloro-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Chloro-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine(1131410-85-9)
• EPA Substance Registry System: 7-Chloro-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine(1131410-85-9)

Safety Data

• Hazardous Substances Data: 1131410-85-9(Hazardous Substances Data)

Usage

General Description

7-Chloro-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine is a chemical compound recognized by its systematic name. The unique aspect of this compound is its structure, which includes a triazolo and pyridin group, both of which are common in pharmaceutical drugs due to their heterocyclic nature. This chemical has yet not as such been investigated thoroughly for any specific pharmacological activity, bioactivity or industrial application. Its properties and implications are largely unexplored, making it a potential subject for future chemical, pharmaceutical or bio-chemical research.

Upstream product

• 19798-80-2 2-Amino-4-chloropyridine 
• 1131410-83-7 ethyl [(4-chloropyridin-2-yl)carbamothioyl]carbamate 

Downstream Products

• 1427452-48-9 7-chloro-[1,2,4]triazolo[1,5-a]pyridine 

Relevant articles and documents

TRIAZOLOPYRIDINE COMPOUNDS USEFUL AS PESTICIDES

The present disclosure provides a novel triazolopyridine compound as represented by formula (I) or a salt thereof that controls pests: wherein, R1 and R3 independently represent hydrogen, or the like; R2 represents C1-C6 alkyl, C3-C8 cycloalkyl, C1-C6 alkoxy, or the like; R4, R5, R7, and R8 independently represent hydrogen, halogen, or the like; R6 represents C1-C6 haloalkoxy, or the like; and Z represents an oxygen atom, a sulfur atom, SO, or SO2.

NOVEL COMPOUNDS FOR THE TREATMENT OF CANCER

The present invention relates to novel compounds showing an inhibitory effect on Mps-1 kinase, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, as well as to intermediate compounds useful in the preparation of said compounds.

DNA gyrase (GyrB)/topoisomerase IV (ParE) inhibitors: Synthesis and antibacterial activity

The synthesis and antibacterial activities of three chemotypes of DNA supercoiling inhibitors based on imidazolo[1,2-a]pyridine and [1,2,4]triazolo[1,5-a]pyridine scaffolds that target the ATPase subunits of DNA gyrase and topoisomerase IV (GyrB/ParE) is reported. The most potent scaffold was selected for optimization leading to a series with potent Gram-positive antibacterial activity and a low resistance frequency.