1131427-22-9

Basic information

• Product Name: 2-(4-methylbenzoylaminomethylthio)-1H-indole
• Synonyms: 2-(4-methylbenzoylaminomethylthio)-1H-indole
• CAS NO: 1131427-22-9
• Molecular Weight: 296.393
• Mol File: 1131427-22-9.mol

Chemical Properties

• CAS DataBase Reference: 2-(4-methylbenzoylaminomethylthio)-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methylbenzoylaminomethylthio)-1H-indole(1131427-22-9)
• EPA Substance Registry System: 2-(4-methylbenzoylaminomethylthio)-1H-indole(1131427-22-9)

Safety Data

• Hazardous Substances Data: 1131427-22-9(Hazardous Substances Data)

Upstream product

• 1060654-17-2 (4-methylbenzoylaminomethyl)triethylammonium chloride 
• 496-30-0 indolin-2-thione 
• 1060654-23-0 3-(4-methylbenzoylamino)methylthio-1H-indole 

Downstream Products

• 1131427-32-1 2-(4-methylthiobenzoylaminomethylthio)-1H-indole 

Relevant articles and documents

An expeditious synthesis for γ-carboline analogue 4-aryl-1,3-thiazino[6,5-b]indole derivatives via the trifluoromethanesulfonic acid-promoted isomerization of 3-amidomethylthioindole intermediates to 2-indolyl sulfides

A highly efficient trifluoromethanesulfonic acid-mediated rearrangement of the benzoylaminomethylthio group of 3-benzoylaminomethylthioindoles (7a-e) to position 2 of the indole ring was developed. Thus, 2-benzoylaminomethylthioindoles (9a-e) were obtained in good yields and were involved as key intermediates in the synthesis of the new γ-carboline analogue ring system: 2,9-dihydro-4-aryl-1,3-thiazino[6,5-b]indole derivatives (11a-e). The target thiazinoindoles (11a-e) were prepared via 2-thiobenzoylaminomethylindoles (10a-e) in modified Bischler-Napieralski reactions.