1131604-99-3 Usage
General Description
5-bromo-4-chloropyridine-2,3-diamine is a chemical compound with the molecular formula C5H5BrClN4. It is a diamine derivative of pyridine, containing both bromine and chlorine substituents. 5-bromo-4-chloropyridine-2,3-diamine is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. It is also utilized in the development of novel materials and in chemical research. The presence of both bromine and chlorine atoms in its structure makes 5-bromo-4-chloropyridine-2,3-diamine a versatile building block for the synthesis of a wide range of complex and diverse chemical compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 1131604-99-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,3,1,6,0 and 4 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1131604-99:
(9*1)+(8*1)+(7*3)+(6*1)+(5*6)+(4*0)+(3*4)+(2*9)+(1*9)=113
113 % 10 = 3
So 1131604-99-3 is a valid CAS Registry Number.
1131604-99-3Relevant articles and documents
Discovery and analgesic evaluation of 8-chloro-1,4-dihydropyrido[2,3- b ]pyrazine-2,3-dione as a novel potent d -amino acid oxidase inhibitor
Xie, Dongsheng,Lu, Jun,Xie, Jin,Cui, Junjun,Li, Teng-Fei,Wang, Yan-Chao,Chen, Yuan,Gong, Nian,Li, Xin-Yan,Fu, Lei,Wang, Yong-Xiang
, p. 19 - 32 (2016)
A series of 5-azaquinoxaline-2,3-dione derivatives were synthesized and evaluated on d-amino acid oxidase (DAAO) inhibition as potential α-hydroxylactam-based inhibitors. The potent inhibitory activities in vitro suggested that 5-nitrogen could significantly enhance the binding affinity by strengthening relevant hydrogen bond interactions. The analgesic effects of intrathecal and systemic injection of 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione, a representative molecule of 5-azaquinoxaline-2,3-dione, were investigated in rodents. This research not only confirmed the analgesic effect of the DAAO inhibitors but provided a new class of chemical entities with oral application potential for the treatment of chronic pain and morphine analgesic tolerance.
