113162-46-2

Basic information

• Product Name: 2,3-DIHYDRO-1H-INDOLE-5-SULFONIC ACID METHYLAMIDE
• Synonyms: BUTTPARK 120\07-99;2,3-DIHYDRO-1H-INDOLE-5-SULFONIC ACID METHYLAMIDE
• CAS NO: 113162-46-2
• Molecular Formula: C9H12N2O2S
• Molecular Weight: 212.27
• Mol File: 113162-46-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 123-124 °C
• Boiling Point: 395.8±52.0 °C(Predicted)
• Appearance: /
• Density: 1.285±0.06 g/cm3(Predicted)
• PKA: 12.54±0.20(Predicted)
• CAS DataBase Reference: 2,3-DIHYDRO-1H-INDOLE-5-SULFONIC ACID METHYLAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIHYDRO-1H-INDOLE-5-SULFONIC ACID METHYLAMIDE(113162-46-2)
• EPA Substance Registry System: 2,3-DIHYDRO-1H-INDOLE-5-SULFONIC ACID METHYLAMIDE(113162-46-2)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 113162-46-2(Hazardous Substances Data)

Usage

General Description

2,3-Dihydro-1H-indole-5-sulfonic acid methylamide is a chemical compound with the molecular formula C9H10N2O2S. It is a sulfonamide derivative of indole and is commonly used in the synthesis of various organic compounds. 2,3-DIHYDRO-1H-INDOLE-5-SULFONIC ACID METHYLAMIDE has a wide range of applications, including in the pharmaceutical industry for the production of potential drug candidates and in chemical research for the development of new materials. It is also used as an intermediate in the synthesis of dyes, pigments, and other organic compounds. Additionally, 2,3-Dihydro-1H-indole-5-sulfonic acid methylamide has been studied for its potential biological activities, such as its anti-inflammatory and anti-cancer properties.

Upstream product

• 113162-45-1 5-(methylsulfamoyl)-N-acetylindoline 
• 52206-05-0 1-acetyl-2,3-dihydro-1H-indole-5-sulfonyl chloride 
• 16078-30-1 1-Acetyl-2,3-dihydro-1H-indole 

Relevant articles and documents

Diarylsulfonylureas for use in treating secretory diarrhea

This invention provides methods of treating secretory diarrhea or cystic fibrosis in a mammal which comprises administering to a mammal in need thereof an effective amount of diarylsulfonylurea. This invention also describes specific diarylsulfonylureas f

Indole-sulfonamides as antitumor agents

This invention provides certain indolinesulfonamide and substituted-indolesulfonamide derivatives of the formula wherein: R1 is C1-C6 alkyl;, R2 and R3 are independently selected from the group consisting of hydrogen, halo, C1-C6 alkyl, and trifluoromethyl, provided that no more than one of R2 and R3 can be hydrogen;, and methods for using them in the treatment of susceptible neoplasms in mammals. Also provided are certain novel pharmaceutical formulations employing these indolinesulfonamide and substituted-indolesulfonamide derivatives in combination with a carrier, excipient or diluent, as well as processes for preparing the compounds.

Regioselectivity of Electrophilic Aromatic Substitution: Syntheses of 6- and 7-Sulfamoylindolines and -indoles

The previously reported chlorosulfonation of 1-acetyl-5-bromoindoline at the 7-position is in error.In actuality, the 6-substituted product is the sole regioisomer produced.This regiochemical assignment is based on NMR data and confirmed by X-ray analysis.We have prepared the first 7-sulfamoylindoline and the corresponding indole from indoline using the indoline nitrogen to direct sulfamoylation intarmolecularly to the 7-position.The new 7-substituted derivatives may prove to be important as intermediates to indole-based dyes and as herbicides.