Cas 1131735-48-2,6-({2,6-dichloro-4-[5-(1-hydroxy-1-methylethyl)-1,2,4-oxadiazol-3-yl]phenyl}amino)pyrido[4,3-c]-1,6-naphthyridin-10(9H)-one

1131735-48-2

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Product Name: 6-({2,6-dichloro-4-[5-(1-hydroxy-1-methylethyl)-1,2,4-oxadiazol-3-yl]phenyl}amino)pyrido[4,3-c]-1,6-naphthyridin-10(9H)-one
Synonyms: 6-({2,6-dichloro-4-[5-(1-hydroxy-1-methylethyl)-1,2,4-oxadiazol-3-yl]phenyl}amino)pyrido[4,3-c]-1,6-naphthyridin-10(9H)-one
CAS NO:1131735-48-2
Molecular Formula:
Molecular Weight: 483.313
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 6-({2,6-dichloro-4-[5-(1-hydroxy-1-methylethyl)-1,2,4-oxadiazol-3-yl]phenyl}amino)pyrido[4,3-c]-1,6-naphthyridin-10(9H)-one(CAS DataBase Reference)
NIST Chemistry Reference: 6-({2,6-dichloro-4-[5-(1-hydroxy-1-methylethyl)-1,2,4-oxadiazol-3-yl]phenyl}amino)pyrido[4,3-c]-1,6-naphthyridin-10(9H)-one(1131735-48-2)
EPA Substance Registry System: 6-({2,6-dichloro-4-[5-(1-hydroxy-1-methylethyl)-1,2,4-oxadiazol-3-yl]phenyl}amino)pyrido[4,3-c]-1,6-naphthyridin-10(9H)-one(1131735-48-2)

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Hazard Codes: N/A
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Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1131735-48-2(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1131735-48-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,3,1,7,3 and 5 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1131735-48:
(9*1)+(8*1)+(7*3)+(6*1)+(5*7)+(4*3)+(3*5)+(2*4)+(1*8)=122
122 % 10 = 2
So 1131735-48-2 is a valid CAS Registry Number.

1131735-48-2Upstream product

1131737-24-0 1-{3-(3,5-dichloro-4-[(10-ethoxypyrido[4,3-c]-1,6-naphthyridin-6-yl)amino]phenyl)-1,2,4-oxadiazol-5-yl}-1-methylethyl acetate

1131735-48-2Downstream Products

1131735-48-2Relevant academic research and scientific papers

INHIBITORS OF JANUS KINASES

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Page/Page column 109, (2009/04/25)

The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2) and PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3 TYK2 and PDK1 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer.

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