1131849-72-3Relevant academic research and scientific papers
Synthesis of chemical-biology tools enabling in vivo imaging and analysis of epigallocatechin gallate
Asakawa, Tomohiro,Yoshida, Atsushi,Hirooka, Yasuo,Suzuki, Takashi,Itoh, Kunihiko,Shimizu, Kosuke,Oku, Naoto,Furuta, Takumi,Wakimoto, Toshiyuki,Inai, Makoto,Kan, Toshiyuki
, p. 218 - 242 (2017/03/14)
(-)-Epigallocatechin gallate (EGCg) has multiple bioactivities, and imaging/analytical tools are required for drug development studies. Here we present full details of our synthetic studies aimed at providing building blocks for development of such tools,
Efficient synthesis of optically active gallocatechin-3-gallate derivatives via 6-endo-cyclization
Hirooka, Yasuo,Nitta, Mariko,Furuta, Takumi,Kan, Toshiyuki
scheme or table, p. 3234 - 3238 (2009/06/18)
Optically active dihydrobenzopyran derivatives are synthesized by 6-endo cyclization of corresponding epoxy-phenol, which is readily derived from the enantioselective epoxidation of 1,3-diarylpropene. Synthetic dihydrobenzopyrans are converted into (-)-5,7-dideoxy-gallocatechin gallate as well as (-)-5,7-dideoxy-epigallocatechin derivative. Georg Thieme Verlag Stuttgart.
