113239-29-5Relevant academic research and scientific papers
Discovery of glutathione S-transferase inhibitors using dynamic combinatorial chemistry
Shi, Baolu,Stevenson, Ross,Campopiano, Dominic J.,Greaney, Michael F.
, p. 8459 - 8467 (2006)
Protein-directed dynamic combinatorial chemistry (DCC) relies on reversible chemical reactions that can function under the near-physiological conditions required by the biological target. Few classes of reaction have so far proven effective at generating
Compounds useful in treating sickle cell anemia
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, (2008/06/13)
The present invention is directed to compounds of the general formula I and pharmaceutically acceptable salts thereof: STR1 wherein R=H or lower alkyl; R'=H, lower alkyl, benzyl, CH2 OH; A=(CH2)1 to 5, >C(CH3)s
