113243-30-4

Upstream product

• 117200-83-6 6,8-difluoro-1,2,3,4-tetrahydrocarbazol-1-yl-acetic acid 
• 622-95-7 4-chlorobenzyl bromide 

Downstream Products

• 117200-40-5 9-p-Chlorobenzyl-6,8-difluoro-1,2,3,4-tetrahydrocarbazol-1-yl-acetic acid, methyl ester 

Relevant academic research and scientific papers

Tetrahydrocarbazole esters, pharmaceutical compositions and use

Tetrahydrocarbazole esters are disclosed. The compounds act as prostaglandin and thromboxane antagonists and are useful in treating asthma, diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion and dysmenorrhea and nephrotoxicity caused by cyclosporin A and as cytoprotective agents.

Tetrahydrocarbazole 1-alkanoic acids, pharmaceutical compositions and use

Tetrahydrocarbazole 1-alkanoic acids are disclosed. The compounds act as prostaglandin and thromboxane antagonists and are useful in treating asthma, diarrhea, hypertension, angina, platlet aggregation, cerebral spasm, premature labor, spontaneous abortio

Tetrahydrocarbazoles for the improvement of cyclosporin therapy

Tetrahydrocarbazoles, especially Tetrahydrocarbazole-1-alkanoic acids are disclosed. The compounds are useful for improving cyclosporine therapy. In particular, the compounds are useful for limiting cyclosporine induced nephrotoxicity which comprises the