113246-89-2

Upstream product

• 35978-39-3 5-phenylthieno<2,3-d>pyrimidine-4(3H)one 
• 182198-35-2 4-chloro-5-phenyl-thieno[2,3-d]pyrimidine 
• 4815-36-5 ethyl 2-amino-4-phenyl-thiophene-3-carboxylate 
• 113246-86-9 4-Hydrazino-5-phenylthieno<2,3-d>pyrimidine 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 77995-44-9 5-Methyl-9-phenyl-1,2,4-triazolo<1,5-c>thieno<3,2-e>pyrimidine 
• 113246-91-6 5-Chloromethyl-9-phenyl-1,2,4-triazolo<1,5-c>thieno<3,2-e>pyrimidine 
• 113246-90-5 2-Amino-4-phenyl-3-(1H-1,2,4-triazol-3-yl)thiophene 

Relevant academic research and scientific papers

Synthesis and application of some new thienopyrimidine derivatives as antimicrobial agents

The paper describes the synthesis of a new ring system 5-phenylthieno[2,3-d]pyrimidine-4(3H)one (2). Chlorination of (2) with PCl5, POCl3 gave the corresponding 4-chloro derivative (4). Several derivatives of the latter compound have been synthesised and tested for antimicrobial activity.

Studies on the Synthesis and Interconversion of Isomeric Triazolothienopyrimidines. Part III. Cyclization Reactions of 2-Amino-3-(1H-1,2,4-triazol-3-yl)thiophenes

Isolation of 2-amino-3-(1H-1,2,4-triazol-3-yl)thiophenes in the hydrolytic cleavage reactions of isomeric triazolothienopyrimidines is reported.The 2-amino-3-triazolylthiophenes on reaction with one carbon donors were found to cyclize to 1,2,4-triazolothienopyrimidines, exclusively.