113249-04-0Relevant academic research and scientific papers
A REACTIVITY UMPOLUNG ROUTE TO CYCLIC HOMOENOLATE ALDOL PRODUCTS VIA α-ALKOXYORGANOCUPRATE CONJUGATE ADDITIONS.
Linderman, Russell J.,Godfrey, Alex,Horne, Kelly
, p. 3911 - 3914 (1987)
Substituted α-alkoxyorganocuprate reagents readily undergo conjugate addition reactions with cyclic enones to provide homoaldol products.
APPLICATIONS OF α-ALKOXYORGANOCUPRATE REAGENTS IN THE REGIOSPECIFIC SYNTHESIS OF CYCLIC HOMOALDOL PRODUCTS
Linderman, Russell J.,Godfrey, Alex,Horne, Kelly
, p. 495 - 506 (2007/10/02)
Cyclic homoaldol products have been prepared via conjugate addition of α-alkoxyorganocuprate reagents to enones.The reactions are regiospecific, providing the homoaldol products in good to excellent yields.The preparation of the cuprates from the α-alkoxyorganostannane precursor is described in detail.Best results were obtained with the higher order cyano cuprate reagent using in-situ trimethylsilyl chloride.
