113249-07-3Relevant academic research and scientific papers
1,4-Addition of Optically Active Transferable Ligands from Organocuprates. Generation and Reaction of Homochiral α-Alkoxyorganocuprates
Linderman, Russell J.,Griedel, Brian D.
, p. 5428 - 5430 (2007/10/02)
Homochiral higher order cyano α-alkoxyorganocuprate addition to ynoates and enones occurs with 0-97percent retention of configuration; results that imply multiple reaction pathways may be operative in 1,4-addition of these species.
APPLICATIONS OF α-ALKOXYORGANOCUPRATE REAGENTS IN THE REGIOSPECIFIC SYNTHESIS OF CYCLIC HOMOALDOL PRODUCTS
Linderman, Russell J.,Godfrey, Alex,Horne, Kelly
, p. 495 - 506 (2007/10/02)
Cyclic homoaldol products have been prepared via conjugate addition of α-alkoxyorganocuprate reagents to enones.The reactions are regiospecific, providing the homoaldol products in good to excellent yields.The preparation of the cuprates from the α-alkoxyorganostannane precursor is described in detail.Best results were obtained with the higher order cyano cuprate reagent using in-situ trimethylsilyl chloride.
A REACTIVITY UMPOLUNG ROUTE TO CYCLIC HOMOENOLATE ALDOL PRODUCTS VIA α-ALKOXYORGANOCUPRATE CONJUGATE ADDITIONS.
Linderman, Russell J.,Godfrey, Alex,Horne, Kelly
, p. 3911 - 3914 (2007/10/02)
Substituted α-alkoxyorganocuprate reagents readily undergo conjugate addition reactions with cyclic enones to provide homoaldol products.
