1132641-29-2

Basic information

• Product Name: methyl 2-(((tertbutoxycarbonyl)oxy)(4-chlorophenyl)methyl)acrylate
• Synonyms: methyl 2-(((tertbutoxycarbonyl)oxy)(4-chlorophenyl)methyl)acrylate
• CAS NO: 1132641-29-2
• Molecular Weight: 326.777
• Mol File: 1132641-29-2.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: methyl 2-(((tertbutoxycarbonyl)oxy)(4-chlorophenyl)methyl)acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(((tertbutoxycarbonyl)oxy)(4-chlorophenyl)methyl)acrylate(1132641-29-2)
• EPA Substance Registry System: methyl 2-(((tertbutoxycarbonyl)oxy)(4-chlorophenyl)methyl)acrylate(1132641-29-2)

Safety Data

• Hazardous Substances Data: 1132641-29-2(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 131469-67-5 methyl 2-[1-hydroxy-1-(4-chlorophenyl)methyl]acrylate 

Downstream Products

• 1132641-39-4 C₂₃H₁₇ClN₂O₂S 
• 1132641-60-1 C₂₃H₁₇ClN₂O₂S 
• 1202888-72-9 methyl (R)-2-{(4-chlorophenyl)[1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl]methyl}acrylate 
• 1210327-91-5 C₂₁H₁₆Cl₂O₄ 
• 1228338-53-1 (R)-methyl 2-((4-chlorophenyl)(diphenylphosphoryl)methyl)acrylate 
• 1236226-90-6 (R)-methyl 2-((4-chlorophenyl)(diethylphosphoryl)methyl)acrylate 
• 1279575-80-2 (1S,4R,5S)-1',5-di-tert-butyl 3-methyl 4-(4-chlorophenyl)-2'-oxospiro[cyclopent[2]ene-1,3'-indoline]-1',3,5-tricarboxylate 
• 1279575-79-9 (1S,4R,5S)-1'-tert-butyl 3,5-dimethyl 4-(4-chlorophenyl)-2'-oxospiro[cyclopent[2]ene-1,3'-indoline]-1',3,5-tricarboxylate 
• 1279575-45-9 (1S,4R,5S)-dimethyl-4-(4-chlorophenyl)-2'-oxo-1'-(phenylcarbamoyl)spiro[cyclopent[2]ene-1,3'-indoline]-3,5-dicarboxylate 
• 1279575-76-6 (1S,4R,5R)-methyl 4-(4-chlorophenyl)-2'-oxo-5-phenyl-1'-(phenylcarbamoyl)spiro[cyclopent[2]ene-1,3'-indoline]-3-carboxylate 
• 1279575-59-5 (1S,4R,5S)-5-benzyl 3-methyl 4-(4-chlorophenyl)-2'-oxo-1'-(phenylcarbamoyl)spiro[cyclopent[2]ene-1,3'-indoline]-3,5-dicarboxylate 
• 1279575-61-9 (1S,4R,5S)-methyl 5-benzoyl-4-(4-chlorophenyl)-2'-oxo-1'-(phenylcarbamoyl)spiro[cyclopent[2]ene-1,3'-indoline]-3-carboxylate 

Relevant articles and documents

Phosphine-Catalyzed [3 + 2] Annulation of Morita-Baylis-Hillman Carbonates with Isoxazole-Based Alkenes

A phosphine-catalyzed [3 + 2] annulation of Morita-Baylis-Hillman (MBH) carbonates with 3-methyl-4-nitro-5-styrylisoxazoles has been developed to afford various multifunctional isoxazoles in moderate to good yields with moderate to excellent diastereoselectivities. With a spirocyclic chiral phosphine as the catalyst, up to 89% ee was obtained.

Synthesis of β-Lactams via Enantioselective Allylation of Anilines with Morita-Baylis-Hillman Carbonates

Enantioenriched β-lactams are accessed via enantioselective allylation of anilines with Morita-Baylis-Hillman carbonates followed by a base-promoted cyclization. The resulting 3-methyleneazetidin-2-ones are amenable to diastereoselective functionalization

Direct Synthesis of Dihydropyrrolo[2,1-a]Isoquinolines through FeCl3 Promoted Oxidative Aromatization

We have developed a straightforward FeCl3 promoted synthesis of dihydropyrrolo[2,1-a]isoquinolines through formal (3+2) cycloaddition/oxidative aromatization cascade of dihydroisoquinoline with Morita-Baylis-Hillman carbonates (up to 96% yield)