1132667-81-2Relevant academic research and scientific papers
Direct aza-darzens aziridination of N-tosylimines with 2-bromomalonates for the synthesis of highly functionalized donor-acceptor aziridines
Wu, Xingxing,Li, Lei,Zhang, Junliang
, p. 3485 - 3489 (2013/02/22)
An approach to highly functionalized donor-acceptor aziridines by the aziridination of N-tosylimines and 2-bromomalonates in the presence of sodium hydride under mild conditions has been developed. The high-yielding reaction has a relatively broad scope and can be easily scaled up to the gram level.
Iodobenzene diacetate/tetrabutylammonium iodide-induced aziridination of N-tosylimines with activated methylene compounds under mild conditions
Fan, Renhua,Ye, Yang
scheme or table, p. 1526 - 1530 (2009/07/01)
Aziridination of N-tosylimines with activated methylene compounds induced by iodobenzene diacetate [PhI(OAc)2] and tetrabutylammonium bromide [Bu4NBr] afforded the corresponding 2,2-difunctionalized aziridines in good yields with the aid of a catalytic amount of base. The reaction is hypothesized to proceed via a tandem nucleophilic addition-oxidative cyclization pathway.
