1132671-72-7Relevant academic research and scientific papers
Synthesis and CHK1 inhibitory potency of Hymenialdisine analogues
Parmentier, Jean-Gilles,Portevin, Bernard,Golsteyn, Roy M.,Pierré, Alain,Hickman, John,Gloanec, Philippe,De Nanteuil, Guillaume
scheme or table, p. 841 - 844 (2009/08/07)
A series of thieno[3,2-b]pyrroloazepinones derivatives related to Hymenialdisine were prepared and tested for CHK1 inhibitory activity. Nanomolar inhibitions were achieved when electron-withdrawing substituents were introduced at position 3 of the thiophene ring.
