1132701-98-4

Basic information

• Product Name: (R)-3-(4-bromo-2,5-dimethoxyphenyl)-1,2-propanediol
• Synonyms: (R)-3-(4-bromo-2,5-dimethoxyphenyl)-1,2-propanediol
• CAS NO: 1132701-98-4
• Molecular Weight: 291.142
• Mol File: 1132701-98-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-3-(4-bromo-2,5-dimethoxyphenyl)-1,2-propanediol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-(4-bromo-2,5-dimethoxyphenyl)-1,2-propanediol(1132701-98-4)
• EPA Substance Registry System: (R)-3-(4-bromo-2,5-dimethoxyphenyl)-1,2-propanediol(1132701-98-4)

Safety Data

• Hazardous Substances Data: 1132701-98-4(Hazardous Substances Data)

Upstream product

• 1132701-96-2 3-(4-bromo-2,5-dimethoxyphenyl)propanal 
• 1246659-57-3 (R)-4-(4-bromo-2,5-dimethoxybenzyl)-2-methyl-1,3-dioxolane 

Downstream Products

• 1132702-07-8 C₁₈H₂₁BrO₆S 
• 1246659-57-3 (R)-4-(4-bromo-2,5-dimethoxybenzyl)-2-methyl-1,3-dioxolane 

Relevant articles and documents

Intra- And intermolecular oxa-pictet-spengler cyclization strategy for the enantioselective synthesis of deoxy analogues of (+)-nanomycin A methyl ester, (+)-eleutherin, (+)-allo-eleutherin, and (+)-thysanone

Enantioselective synthesis of deoxy analogues of pyranonaphthoquinone antibiotics (+)-nanomycin A methyl ester, (+)eleutherin, (+)-allo-eleutherin, and (+)-thysanone was achieved in good overall yield with high enantio- and diastereoselectivity from the common intermediate (R)-3-(2,5-dimethoxyph.enyl) propane-1,2-diol. The intramolecular oxaPictet-Spengler cyclization of 6-a:ryl-l.,3-dioxolone was de-veloped for the first time and utilized in the enantioselective synthesis of (H-)-deoxynanomycin A methyl ester, whereas the intermolecular oxa-Pictet-Spengler cycllzation strategy was applied to the enantioselective synthesis of deoxy analogues of (+)-eleutherm, (+)-allo-eleutherin, and. (+)-thysanone,

Organocatalytic enantioselective formal synthesis of HRV 3C-protease inhibitor (1R,3S)-thysanone

A short and efficient organocatalytic enantioselective formal synthesis of HRV 3C-protease inhibitor (1R,3S)-thysanone is achieved in a nine-step with 98.7% enantiomeric excess, by employing l-proline-catalyzed asymmetric α-aminooxylation of aldehyde and