1132702-00-1Relevant academic research and scientific papers
Organocatalytic approach to (s)-1-arylpropan-2-ols: Enantioselective synthesis of the key intermediate of antiepileptic agent (-)-talampanel
Sawant, Rajiv T.,Waghmode, Suresh B.
experimental part, p. 2269 - 2277 (2010/09/11)
An efficient organocatalytic route for the preparation of enantioselective synthesis of (S)-1-arylpropan-2-ols derivatives, including the key intermediate of antiepileptic agent (-)-talampanel is described. The key steps involved are L-proline-catalyzed a
Organocatalytic enantioselective formal synthesis of HRV 3C-protease inhibitor (1R,3S)-thysanone
Sawant, Rajiv T.,Waghmode, Suresh B.
experimental part, p. 1599 - 1602 (2009/05/09)
A short and efficient organocatalytic enantioselective formal synthesis of HRV 3C-protease inhibitor (1R,3S)-thysanone is achieved in a nine-step with 98.7% enantiomeric excess, by employing l-proline-catalyzed asymmetric α-aminooxylation of aldehyde and
