1132783-30-2Relevant academic research and scientific papers
Si-OSO3H catalyzed one-pot three-component synthesis of 1,3-oxazines
Sudha,Pasha
, p. 1533 - 1536 (2015/02/05)
A simple and an efficient method for the synthesis of six membered nitrogen containing heterocyclic compounds - 1,3-oxazines from diethyl acetylene dicarboxylate, substituted anilines or amines and formaldehyde is reported. A versatile, economical and eco
Ytterbium triflate promoted one-pot three component synthesis of 3,4,5-trisubstituted-3,6-dihydro-2H-1,3-oxazines
Epifano, Francesco,Pelucchini, Caroline,Rosati, Ornelio,Genovese, Salvatore,Curini, Massimo
experimental part, p. 844 - 849 (2012/02/14)
An efficient one-pot synthesis of 3,4,5-trisubstituted-3,6-dihydro-2H-1,3- oxazines from acetylene dicarboxylates, aromatic and aliphatic amines, and formaldehyde is described. The six member N,O-heterocyclic nucleus was constructed via Yb(OTf)3/sub
Synthesis of substituted 1,3-oxazines using sulfamic acid as an efficient and eco-friendly catalyst
Damodiran,Perumal, Paramasivan T.
experimental part, p. 1386 - 1391 (2011/02/22)
Sulfamic acid catalyzed the synthesis of substituted 1,3-oxazines by one-pot three-component reaction of aniline, alkynoates, and formaldehyde in excellent yields. The catalyst possesses distinct advantages shows ease of handling, good yields, cleaner rea
L-Proline-catalyzed synthesis of highly functionalized multisubstituted 1,4-dihydropyridines
Jiang, Huanfeng,Mai, Ronghuan,Cao, Hua,Zhu, Qiuhua,Liu, Xiaohang
scheme or table, p. 4943 - 4953 (2010/02/16)
Highly functionalized multisubstituted 1,4-dihydropyridines 5 have been concisely synthesized in moderate to good yields vial-proline-catalyzed one-pot multicomponent reactions (MCRs) of alkynoates or alkynones 1, amines 2, β-dicarbonyl compounds 3 and aldehydes 4 under mild conditions. The MCR process involves hydroamination/Knoevenagel condensation/Michael-type addition/intramolecular cyclization processes and leads to the formation of 1,4-dihydropyridines 5. The molecular structure of 5ckaa was confirmed by single-crystal X-ray diffraction. This method is energy saving and environmentally friendly, providing easy access to diverse multisubstituted polyfunctional 1,4-dihydropyridines. The Royal Society of Chemistry 2009.
Br?nsted acid-promoted domino reactions: a novel one-pot three-component synthesis of 3,4,5-trisubstituted-3,6-dihydro-2H-1,3-oxazines
Cao, Hua,Jiang, Huan-Feng,Qi, Chao-Rong,Yao, Wen-Juan,Chen, Huo-Ji
scheme or table, p. 1209 - 1214 (2009/05/27)
An efficient and novel one-pot synthesis of 3,4,5-trisubstituted-3,6-dihydro-2H-1,3-oxazine from alkynoates, anilines, and formaldehyde is described. The six-membered N,O-heterocyclic skeleton was constructed via Br?nsted acid-promoted domino hydroaminati
