1132814-49-3 Usage
General Description
2-(1-aminocyclobutyl)ethan-1-ol, also known as ACBOH, is a chemical compound that belongs to the class of amines. It consists of a cyclobutyl ring with an amino group at the first carbon, attached to an ethyl group and a hydroxyl group. 2-(1-aminocyclobutyl)ethan-1-ol is used in organic synthesis and pharmaceutical research as a building block for more complex molecules. It is also used as a reagent in chemical reactions and as a precursor for the synthesis of various pharmaceuticals. ACBOH has potential applications in the development of new drugs and in the production of fine chemicals. It is important to handle this compound with care, as it can be hazardous if not properly managed.
Check Digit Verification of cas no
The CAS Registry Mumber 1132814-49-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,3,2,8,1 and 4 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1132814-49:
(9*1)+(8*1)+(7*3)+(6*2)+(5*8)+(4*1)+(3*4)+(2*4)+(1*9)=123
123 % 10 = 3
So 1132814-49-3 is a valid CAS Registry Number.
1132814-49-3Relevant articles and documents
Quinolone derivatives containing strained spirocycle as orally active glycogen synthase kinase 3β (GSK-3β) inhibitors for type 2 diabetics
Seto, Shigeki,Yumoto, Kazuhiko,Okada, Kyoko,Asahina, Yoshikazu,Iwane, Aya,Iwago, Maki,Terasawa, Reiko,Shreder, Kevin R.,Murakami, Koji,Kohno, Yasushi
, p. 1188 - 1200 (2012/03/26)
The design, synthesis, and evaluation of 6-6-7 tricyclic quinolones containing the strained spirocycle moiety aiming at the GSK-3β inhibitor were described. Among the synthesized compounds, 44, having a cyclobutane ring on a spirocycle, showed excellent GSK-3β inhibitory activity in both cell-free and cell-based assays (IC50 = 36 nM, EC50 = 3.2 μM, respectively). Additionally, 44 decreased the plasma glucose concentration dose-dependently after an oral glucose tolerance test in mice.
