1132922-53-2Relevant academic research and scientific papers
Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice
LoVerme, Jesse,Duranti, Andrea,Tontini, Andrea,Spadoni, Gilberto,Mor, Marco,Rivara, Silvia,Stella, Nephi,Xu, Cong,Tarzia, Giorgio,Piomelli, Daniele
supporting information; experimental part, p. 639 - 643 (2009/09/06)
Cannabinoid CB1 receptor antagonists reduce body weight in rodents and humans, but their clinical utility as anti-obesity agents is limited by centrally mediated side effects. Here, we describe the first mixed CB1 antagonist/CB2
