113331-83-2

Upstream product

• 113331-82-1 1-bromo-3-phenyl-3-cyclopentene 
• 27856-20-8 1-hydroxy-3-phenylcyclopent-3-ene 
• 29586-29-6 1-acetoxy-3-phenyl-3-cyclopentene 
• 114738-33-9 (1S^*,3R^*,4S^*)-1-acetoxy-3-<(tert-butyldimethylsilyl)oxy>-4-phenylcyclopentane 
• 120624-03-5 (1SR,3SR,4SR)-1-acetoxy-3-bromo-4-phenylcyclopentane 
• 120624-02-4 (1RS,2SR,4SR)-4-acetoxy-2-phenyl-1-cyclopentanol 

Downstream Products

• 113331-85-4 (1S^*,3S^*,4S^*)-4-phenylcyclopentane-1,3-diol 
• 113331-81-0 (1R^*,4R^*,5S^*)-5-phenyl-2,3-dioxabicyclo<2.2.1>heptane 
• 113331-81-0 (1R,4R,5R)-5-Phenyl-2,3-dioxa-bicyclo[2.2.1]heptane 

Relevant academic research and scientific papers

SYNTHESIS OF A PROSTAGLANDIN ENDOPEROXIDE MODEL COMPOUND AND ITS REACTION WITH ELECTRON TRANSFER REAGENTS

5-Exo-phenyl-2,3-dioxabicycloheptane (4c) was synthesized as a model compound of prostaglandin endoperoxide (PGH) to mimic the bioconversion of PGH into thromboxane (TX).The reaction of (4c) with various electron transfer reagents was investigated.With the aid of a catalytic amount of ferrous ion, (4c) was successfully converted into the thromboxane B (TXB) skeleton.

An Electron Transfer Model for Thromboxane Biosynthesis

Conversion of prostaglandin endoperoxide model compound (1) into the thromboxane B ring system (6a) and (7a) was achieved with the aid of the ferrous ion.