1133438-93-3Relevant articles and documents
Synthesis and CB1 cannabinoid receptor affinity of 4-alkoxycarbonyl-1,5-diaryl-1,2,3-triazoles
Shu, Hong,Izenwasser, Sari,Wade, Dean,Stevens, Edwin D.,Trudell, Mark L.
scheme or table, p. 891 - 893 (2009/08/07)
A series of 4-alkoxycarbonyl-1,5-diaryl-1,2,3-triazoles were synthesized regioselectively using click chemistry and evaluated at CB1 cannabinoid receptors. The n-propyl ester 11 (Ki = 4.6 nM) and phenyl ester 14 (Ki = 11 nM) exhibite