113348-70-2Relevant academic research and scientific papers
A Novel Method for the In Situ Generation of Alkoxydialkylboranes and Their Use in the Selective Preparation of 1,3-Syn Diols
Chen, Kau-Ming,Gunderson, Karl G.,Hardtmann, Goetz E.,Prasad, Kapa,Repic, Oljan,Shapiro, Michael J.
, p. 1923 - 1926 (2007/10/02)
An in situ method for generating Et2BOCH3 from triethylborane and methanol without using any other catalysts is described.Using the Et2BOCH3 thus generated as a chelating agent, syn 1,3-diols are prepared in > 98 percent stereochemical purity by reducing β-hydroxy-ketones with sodium borohydride
1,3-SYN DIASTEREOSELECTIVE REDUCTION OF β-HYDROXYKETONES UTILIZING ALKOXYDIALKYLBORANES
Chen, Kau-Ming,Hardtmann, Goetz E.,Prasad, Kapa,Repic, Oljan,Shapiro, Michael J.
, p. 155 - 158 (2007/10/02)
Sodium borohydride reduction of β-hydroxyketones in presence of alkoxydialkylboranes 1-7 as complexing agents, produced 1,3-syn diols in at least 98:2 ratio.As illustrated with examples 8-17 this method is quite general and superior to those described in
