113348-75-7Relevant academic research and scientific papers
Photolysis of α-Tocopherol in Olive Oils and Model Systems
Pirisi, Filippo M.,Angioni, Alberto,Bandino, Giovanni,Cabras, Paolo,Guillou, Claude,Maccioni, Elisabetta,Reniero, Fabiano
, p. 4529 - 4533 (1998)
The photolysis of α-tocopherol (I) in olive oil (O) and in some model systems (n-hexane = H; anhydrous n-hexane = HA, and triolein = T) was studied under sunlight and under artificial light (λ > 290 nm) by HPLC and GC/MS. In O and T, I disappeared linearly to 50% of the starting concentration, reached a constant value, and finally disappeared rapidly from the medium. In the model system, photolysis followed a pseudo-first-order kinetics. Although no peaks attributable to photoproducts were found in O, a main product identified by 1H and 13C NMR and GC/MS as 5-formyltocopherol (II) was found in the model systems. Irradiation of compound II led to species undetectable by HPLC in agreement with a slower consecutive kinetic process than that of I. In the HA and T systems, the formation of II occurred at lower levels than in H. The possible behavior of photodegradation is discussed.
Identification of α-Tocopherol and Its Oxidation Products by Ultra-Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry
Tang, Chuanhui,Tao, Guanjun,Wang, Yue,Liu, Yuanfa,Li, Jinwei
, p. 669 - 677 (2020)
This study aimed to determine α-tocopherol (α-T) and its thermal oxidation products simultaneously. A novel method based on an ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS) was developed. This approach was achieved by means of a BEH C18 analytical column under gradient elution conditions with eluents of acetonitrile/isopropanol (1:9, v/v) and acetonitrile/water (4:6, v/v). Compounds were elucidated through exact molecular mass and fragmentation ions obtained from the Q-TOF-MS detector. Two oxidation products, α-tocopheryl quinone and 5-formyl-?3-tocopherol, were identified, and one new compound was determined. This approach offered a simple, precise, and reliable method to determine oxidation products of α-T, which may give a way to understand the mechanism of the thermal oxidative process of α-T.
Copper(II)-catalyzed oxidation of d-α-tocopherol by oxygen in aqueous solution
Nagata, Yoshiko,Miyamoto, Chie,Matsushima, Yoshikazu,Matsumoto, Shigenobu
, p. 71 - 76 (2000)
α-Tocopherol (α-Toc) was solubilized in aqueous solutions using 13 solubilizing agents and the products of oxidation by oxygen in the presence and the absence of Cu(II) were analyzed by HPLC. In the presence of Cu(II), the oxidation was accelerated and 5-
