113366-43-1

Basic information

• Product Name: 5-methyl-2-phenyl-4-Thiazolecarboxylic acid
• Synonyms: 5-methyl-2-phenyl-4-Thiazolecarboxylic acid;5-methyl-2-phenyl-1,3-thiazole-4-carboxylic acid;5-Methyl-2-phenyl-thiazole-4-carboxylic acid
• CAS NO: 113366-43-1
• Molecular Formula: C₁₁H₉NO₂S
• Molecular Weight: 219.25966
• Mol File: 113366-43-1.mol
• Article Data: 2

Chemical Properties

• Melting Point: 183-185 °C
• Boiling Point: 424.0±37.0 °C(Predicted)
• Appearance: /
• Density: 1.319±0.06 g/cm3(Predicted)
• PKA: 3.76±0.10(Predicted)
• CAS DataBase Reference: 5-methyl-2-phenyl-4-Thiazolecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-2-phenyl-4-Thiazolecarboxylic acid(113366-43-1)
• EPA Substance Registry System: 5-methyl-2-phenyl-4-Thiazolecarboxylic acid(113366-43-1)

Safety Data

• Hazardous Substances Data: 113366-43-1(Hazardous Substances Data)

Upstream product

• 2227-79-4 benzenecarbothioamide 
• 132089-40-8 ethyl 5-methyl-2-phenylthiazole-4-carboxylate 

Downstream Products

• 113378-36-2 5-(3-hydroxypentyl)-2-phenylthiazole-4-carboxylic acid 
• 113366-63-5 5-(2-Hydroxy-2-phenyl-propyl)-2-phenyl-thiazole-4-carboxylic acid 
• 113366-62-4 5-(but-3-enyl)-2-phenylthiazole-4-carboxylic acid 

Relevant articles and documents

CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME

The present invention provides a novel carboxylic acid compound, a salt thereof or a hydrate of them useful as an insulin-resistant improver, and a medicament comprising the compound as an active ingredient. That is, the present invention provides a carboxylic acid compound represented by the following formula (I), a salt thereof, an ester thereof or a hydrate of them. In the formula, R1 represents hydrogen atom, hydroxyl group or a C1-6 alkyl group etc. which may have one or more substituents; L represents a single or double bond or a C1-6 alkylene group etc. which may have one or more substituents; M represents a single bond or a C1-6 alkylene group etc. which may have one or more substituents; T represents a single bond or a C1-3 alkylene group which may have one or more substituents; W represents carboxyl group or a group represented by the formula -CON(Rw1)Rw2 (wherein Rw1 and Rw2 are the same as or different from each other and each represents hydrogen atom, formyl group etc.) etc.; represents a single or double bond; X represents oxygen atom or a C2-6 alkenylene group etc. which may have one or more substituents; Y represents a C5-12 aromatic hydrocarbon group etc. which may have one or more substituents and which may have one or more heteroatoms; and ring Z represents a C5-6 aromatic hydrocarbon group which may have 0 to 4 substituents and which may have one or more heteroatoms.