113366-51-1

Basic information

• Product Name: 5-Oxazolecarboxylicacid,2-ethyl-4-methyl-(9CI)
• Synonyms: 5-Oxazolecarboxylicacid,2-ethyl-4-methyl-(9CI);2-ethyl-4-Methyloxazole-5-carboxylic acid;2-Ethyl-4-methyl-1,3-oxazole-5-carboxylic acid
• CAS NO: 113366-51-1
• Molecular Formula: C₇H₉NO₃
• Molecular Weight: 155.15126
• Product Categories: CARBOXYLICACID
• Mol File: 113366-51-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 286.4±20.0 °C(Predicted)
• Appearance: /
• Density: 1.220±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 3.75±0.20(Predicted)
• CAS DataBase Reference: 5-Oxazolecarboxylicacid,2-ethyl-4-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Oxazolecarboxylicacid,2-ethyl-4-methyl-(9CI)(113366-51-1)
• EPA Substance Registry System: 5-Oxazolecarboxylicacid,2-ethyl-4-methyl-(9CI)(113366-51-1)

Safety Data

• Hazardous Substances Data: 113366-51-1(Hazardous Substances Data)

Upstream product

• 2510-37-4 2,4-dimethyl-oxazole-5-carboxylic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 1477523-91-3 2-(4-(4'-(2-ethyl-4-methyloxazole-5-carboxamido)-[1,1'-biphenyl]-4-yl)-2-oxabicyclo[2.2.2]octan-1-yl)acetic acid 
• 1477524-35-8 methyl 2-(4-(4'-(2-ethyl-4-methyloxazole-5-carboxamido)-[1,1'-biphenyl]-4-yl)-2-oxabicyclo[2.2.2]octan-1-yl)acetate 
• 1477523-93-5 2-(4-(4-(5-(2-ethyl-4-methyloxazole-5-carboxamido)pyridin-2-yl)phenyl)-2-oxabicyclo[2.2.2]octan-1-yl)acetic acid 
• 1477524-34-7 2-ethyl-4-methyl-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)oxazole-5-carboxamide 
• 1005785-55-6 N-[5-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)-2-methylphenyl]-2-ethyl-4-methyl-1,3-oxazole-5-carboxamide 
• 1005785-56-7 N-[5-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)-2-fluorophenyl]-2-ethyl-4-methyl-1,3-oxazole-5-carboxamide 
• 874279-08-0 {4-[2-(4-tert-butyl-phenyl)-1H-benzoimidazol-4-yl]-piperazin-1-yl}-(2-ethyl-4-methyl-oxazol-5-yl)-methanone 
• 137267-42-6 methyl 2-ethyl-4-methyloxazole 5 carboxylate 

Relevant articles and documents

Gonadotropin releasing hormone receptor antagonists

The present invention relates to Gonadotropin Releasing Hormone (“GnRH”) (also known as Leutinizing Hormone Releasing Hormone) receptor antagonists.

NEW METHODS FOR THE HOMOLOGATION OF THIAZOLES AND OXAZOLES BY REGIOSPECIFIC LITHIATIONS OF THIAZOLE- AND OXAZOLE-CARBOXYLIC ACID DERIVATIVES.

Dianions are obtained by regiospecific lithiations of the parent thiazole- and oxazole-carboxylic acids; when the 2-position is blocked by a phenyl group, 4-(or 5-) methyl groups can be lithiated in thiazole- or oxazole-5(or 4-)carboxylic acids .Lithiations of the 2,5-dimethyl isomers are not regiospecific while those of the corresponding N,N-diethylamides give exclusively the monoanions (14) and (17); all of these new intermediates react efficiently with a range of electrophiles.