1133725-45-7Relevant academic research and scientific papers
Novel sulfamides and sulfamates derived from amino esters: Synthetic studies and anticonvulsant activity
Villalba, Maria L.,Enrique, Andrea V.,Higgs, Josefina,Casta?o, Rocío A.,Goicoechea, Sofía,Taborda, Facundo D.,Gavernet, Luciana,Lick, Ileana D,Marder, Mariel,Bruno Blanch, Luis E.
, p. 55 - 63 (2016)
We report herein the design and optimization of a novel series of sulfamides and sulfamates derived from amino esters with anticonvulsant properties. The structures were designed based on the pharmacophoric pattern previously proposed, with the aim of imp
Synthesis and anticonvulsant activity of amino acid-derived sulfamides
Gavernet, Luciana,Elvira, Juan E.,Samaja, Gisela A.,Pastore, Valentina,Cravero, Mariana Sella,Enrique, Andrea,Estiu, Guillermina,Bruno-Blanch, Luis E.
experimental part, p. 1592 - 1601 (2010/02/16)
Sulfamides are promising functions for the design of new antiepileptic drugs (Bioorg. Med. Chem. 2007, 15, 1556-1567; 5604-5614). Following previous research in this line, a set of amino acid-derived sulfamides has been designed, synthesized, and tested a
