Cas 1133784-16-3,Methyl 2-(4-(5-(5-chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)-isoxazole-3-carbonyl)piperazin-1-yl)pyrimidine-5-carboxylate

1133784-16-3

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Basic information

Product Name: Methyl 2-(4-(5-(5-chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)-isoxazole-3-carbonyl)piperazin-1-yl)pyrimidine-5-carboxylate
Synonyms: Methyl 2-(4-(5-(5-chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)-isoxazole-3-carbonyl)piperazin-1-yl)pyrimidine-5-carboxylate
CAS NO:1133784-16-3
Molecular Formula:
Molecular Weight: 565.97
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: Methyl 2-(4-(5-(5-chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)-isoxazole-3-carbonyl)piperazin-1-yl)pyrimidine-5-carboxylate(CAS DataBase Reference)
NIST Chemistry Reference: Methyl 2-(4-(5-(5-chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)-isoxazole-3-carbonyl)piperazin-1-yl)pyrimidine-5-carboxylate(1133784-16-3)
EPA Substance Registry System: Methyl 2-(4-(5-(5-chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)-isoxazole-3-carbonyl)piperazin-1-yl)pyrimidine-5-carboxylate(1133784-16-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1133784-16-3(Hazardous Substances Data)

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1133784-16-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1133784-16-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,3,3,7,8 and 4 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1133784-16:
(9*1)+(8*1)+(7*3)+(6*3)+(5*7)+(4*8)+(3*4)+(2*1)+(1*6)=143
143 % 10 = 3
So 1133784-16-3 is a valid CAS Registry Number.

1133784-16-3Upstream product

1133784-15-2 Methyl 2-(4-(5-(2,4-bis(benzyloxy)-5-chlorophenyl)-4-(4-methoxyphenyl)-isoxazole-3-carbonyl)piperazin-1-yl)pyrimidine-5-carboxylate

1133784-16-3Downstream Products

1133783-64-8 2-(4-(5-(5-chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)isoxazole-3-carbonyl)piperazin-1-yl)-N-hydroxypyrimidine-5-carboxamide

1133784-16-3Relevant academic research and scientific papers

HSP90 INHIBITORS CONTAINING A ZINC BINDING MOIETY

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Page/Page column 30; 40, (2009/04/24)

The present invention relates to HSP90 inhibitors containing a zinc binding moiety and their use in the treatment of cell proliferative diseases such as cancer. The said derivatives may further act as HDAC inhibitors.

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