1133862-70-0

Basic information

• Product Name: 3,5-dinitrobenzylazide
• Synonyms: 3,5-dinitrobenzylazide
• CAS NO: 1133862-70-0
• Molecular Weight: 223.148
• Mol File: 1133862-70-0.mol

Chemical Properties

• CAS DataBase Reference: 3,5-dinitrobenzylazide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-dinitrobenzylazide(1133862-70-0)
• EPA Substance Registry System: 3,5-dinitrobenzylazide(1133862-70-0)

Safety Data

• Hazardous Substances Data: 1133862-70-0(Hazardous Substances Data)

Upstream product

• 99-34-3 3,5-dinitrobenzoic acid 
• 71022-43-0 3,5-dinitrobenzyl alcohol 
• 137570-75-3 1-bromomethyl-3,5-dinitrobenzene 

Downstream Products

• 1133862-71-1 2-[1-(3,5-dinitrobenzyl)-1H-1,2,3-triazol-4-yl]propan-2-ol 

Relevant articles and documents

Inhibition of M. tuberculosis β-ketoacyl CoA reductase FabG4 (Rv0242c) by triazole linked polyphenol-aminobenzene hybrids: Comparison with the corresponding gallate counterparts

Herein we report six novel triazole linked polyphenol-aminobenzene hybrids (3-8) as inhibitors of Mycobacterium tuberculosis FabG4 (Rv0242c), a less explored β-ketoacyl CoA reductase that has immense potential to be the future anti-tuberculosis drug target due to its possible involvement in drug resistance and latent infection. Novel triazole linked polyphenol-aminobenzene hybrids have been synthesized, characterized and evaluated for their inhibitory activity against FabG4. All of them inhibit FabG4 at low micromolar concentrations. In silico docking study has been carried out to explain the experimental findings. A comparative study of these new inhibitors with previously reported gallate counterparts leads to structure-activity relations (SAR) of substituent linked to N-1 of triazole ring.

Copper/HP20: Novel and polymer-supported copper catalyst for huisgen cycloaddition

A polymer-supported copper catalyst (Cu/HP20) is easily prepared in water and effectively catalyzed the Huisgen cycloaddition between azides and terminal alkynes.