1133960-39-0Relevant articles and documents
Stereo-controlled synthesis of novel photoreactive γ-secretase inhibitors
Yang, Guangli,Yin, Ye Ingrid,Chun, Jiong,Shelton, Christopher C.,Ouerfelli, Ouathek,Li, Yue-Ming
experimental part, p. 922 - 925 (2009/10/15)
The stereoselective synthesis of novel photoreactive γ-secretase inhibitors 2 and 3 has been achieved. Key steps of the strategy involve preparation of α-N-Boc-epoxide 8 and formation of lactone 14 in a practical and stereo-controlled fashion. Compounds 2