1134004-74-2Relevant articles and documents
The synthesis of a novel C-nucleoside designed as guanosine analogue
Kourafalos, Vassilios N.,Tite, Tony,Mikros, Emmanuel,Marakos, Panagiotis,Pouli, Nicole,Balzarini, Jan
, p. 3129 - 3132 (2008)
The syntheses of a novel C-nucleoside which can be viewed as 8-aza-3,9-dideazaguanosine, as well as of the corresponding heterocyclic base, are described. N-[4-(2,3,5-tri-O-Acetyl-β-D-ribofuranosylmethyl)-2- methoxypyridin-3-yl]acetamide was regiospecifically nitrated and upon reduction and protection of the amino group underwent ring closure to the corresponding pyrazolopyridine derivative. The guanosine analogue was obtained via successive cleavage of the protecting groups. Georg Thieme Verlag Stuttgart.
