1134099-95-8Relevant academic research and scientific papers
Novel carbohydrate-based thioureas as organocatalysts for asymmetric michael addition of 1,3-dicarbonyl compounds to nitroolefins
Ron?ák, Róbert,Tvrdoňová, Monika,Gonda, Jozef,Ele?ko, Ján
supporting information, (2020/06/24)
A series of novel carbohydrate-derived thioureas were synthesized and examined as catalysts for the asymmetric Michael addition of symmetrical 1,3-dicarbonyl compounds, including dimethyl malonate, to several trans-β-nitrostyrenes. High enantioselectiviti
Synthesis of Chiral Tertiary Amine-Thioureas Based on Spirobi indane and Application in Catalytic Asymmetric Michael Addition Reaction
Han, Zhao,Lin, Xufeng
, p. 1131 - 1139 (2020/04/01)
A series of novel chiral bifunctional tertiary amine-thioureas based on spirobiindane were designed and synthesized as organo catalysts. One of these catalysts was shown to promote the asymmetric Michael addition reaction of 1,3-diphenylpropane-1,3-dione to nitro olefins, affording the desired products in good yields (up to 95%) and enantioselectivities (up to 98% ee).
Recyclable organocatalysis: Highly enantioselective Michael addition of 1,3-diaryl-1,3-propanedione to nitroolefins
Tan, Bin,Zhang, Xuan,Chua, Pei Juan,Zhong, Guofu
supporting information; experimental part, p. 779 - 781 (2009/07/10)
The first Michael addition of 1,3-diaryl-1,3-propanedione to nitroolefins was demonstrated using a simple organocatalyst, which afforded excellent yields (81-97%) and enantioselectivities (90 to >99% ee); the catalyst and excess reactant can be reused sev
