1134099-97-0Relevant academic research and scientific papers
Synthesis of Chiral Tertiary Amine-Thioureas Based on Spirobi indane and Application in Catalytic Asymmetric Michael Addition Reaction
Han, Zhao,Lin, Xufeng
, p. 1131 - 1139 (2020)
A series of novel chiral bifunctional tertiary amine-thioureas based on spirobiindane were designed and synthesized as organo catalysts. One of these catalysts was shown to promote the asymmetric Michael addition reaction of 1,3-diphenylpropane-1,3-dione to nitro olefins, affording the desired products in good yields (up to 95%) and enantioselectivities (up to 98% ee).
MICHAEL REACTION WITH RECOVERY OF THE CATALYST
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Page/Page column 10, (2012/01/14)
Disclosed is a process of carrying out a Michael reaction with recovery of the catalyst, where a compound of formula (1): is reacted with a compound of formula (2): in the presence of a catalyst of formula (4): where the compounds of formulae (1) and (2)
