1134193-64-8

Basic information

• Product Name: 4-(4-methoxyphenyl)-2,6-dimethyl-2H-1,4-benzoxazin-3(4H)-one
• Synonyms: 4-(4-methoxyphenyl)-2,6-dimethyl-2H-1,4-benzoxazin-3(4H)-one
• CAS NO: 1134193-64-8
• Molecular Weight: 283.327
• Mol File: 1134193-64-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(4-methoxyphenyl)-2,6-dimethyl-2H-1,4-benzoxazin-3(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-methoxyphenyl)-2,6-dimethyl-2H-1,4-benzoxazin-3(4H)-one(1134193-64-8)
• EPA Substance Registry System: 4-(4-methoxyphenyl)-2,6-dimethyl-2H-1,4-benzoxazin-3(4H)-one(1134193-64-8)

Safety Data

• Hazardous Substances Data: 1134193-64-8(Hazardous Substances Data)

Upstream product

• 6627-55-0 2-bromo-p-cresol 
• 40781-31-5 2-chloro-N-(4-methoxy-phenyl)propionamide 

Relevant articles and documents

Copper(I)-catalyzed one-pot synthesis of 2H-1,4-benzoxazin-3-(4H)-ones from o-halophenols and 2-chloroacetamides

We developed an efficient and convenient method for preparing N-substituted 2H-1,4-benzoxazin-3-(4H)-ones from 2-halophenols via a nueleophilic substitution with 2-chlo-roacetamides followed by a Cul-catalyzed coupling cyclization. A broad spectrum of substrates can be effectively employed to afford the desired products in good yields. Since this method involves simple reaction conditions, a short reaction time, and a broad substrate scope, it is particularly attractive for the efficient preparation of biologically and medicinally interesting molecules.